About CSSE

Our Approach

Meeting the complexity of modern systems requires an interdisciplinary analytical approach. CSSE researchers combine methods from artificial intelligence, machine learning, data science, and optimization with subject-specific domain expertise to solve humanity’s most complex challenges.

Our Mission

The Center for Systems Science and Engineering (CSSE) at Johns Hopkins University advances research focused on complex real-world challenges, ranging from infectious disease dynamics, the future of energy networks, and the resiliency of urban infrastructure. These problems represent some of humanity’s most important and pressing problems, which cannot be meaningfully understood or addressed in isolation, and require analytical approaches grounded in the broader social, infrastructural, environmental, and technological context. At CSSE we bring together faculty from across disciplines with a common interest in using systems methods to address complex problems.